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CAREER: Defining structural principles for the engineering and evolution of allostery — NSF Award to Johns Hopkins University (MD,

Proteins are nanometer-scale molecules whose composition and shape are specified by genes. Inside the cell, they catalyze chemical reactions, perform mechanical work, and assemble into larger structures. The collective action of very many proteins drives cell growth, division, and movement. Proteins are often controlle

Award titleCAREER: Defining structural principles for the engineering and evolution of allostery
Award ID2606308
AwardeeJohns Hopkins University
CityBALTIMORE
StateMD
Amount obligated$35,719
Principal investigatorKimberly Reynolds
ProgramMolecular Biophysics
Start date10/01/2025
AbstractProteins are nanometer-scale molecules whose composition and shape are specified by genes. Inside the cell, they catalyze chemical reactions, perform mechanical work, and assemble into larger structures. The collective action of very many proteins drives cell growth, division, and movement. Proteins are often controlled by external signals – for example, adding a nutrient to the cellular environment might turn a protein “on” or “off” by binding to the protein and altering its shape or dynamics.
SourceNSF Awards

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