CAREER: How transgenerational chromatin landscapes shape C. elegans cell fate — NSF Award to University of Massachusetts Lowell (M
The experiences of our ancestors can affect our own biology. Studies in animals and humans have shown that stress or environmental exposure can be epigenetically encoded in genomes and inherited for multiple generations. But it is still not clear how epigenetic inheritance occurs, nor what it might mean for descendants
| Award title | CAREER: How transgenerational chromatin landscapes shape C. elegans cell fate |
|---|---|
| Award ID | 2538853 |
| Awardee | University of Massachusetts Lowell |
| City | LOWELL |
| State | MA |
| Amount obligated | $880,000 |
| Principal investigator | Teresa Lee |
| Program | Molecular Biosciences |
| Start date | 06/01/2026 |
| Abstract | The experiences of our ancestors can affect our own biology. Studies in animals and humans have shown that stress or environmental exposure can be epigenetically encoded in genomes and inherited for multiple generations. But it is still not clear how epigenetic inheritance occurs, nor what it might mean for descendants. In cells, genomes are packaged into chromatin, where DNA is wrapped around histone proteins. Modifications are added or removed from histones, controlling how the genome is used |
| Source | NSF Awards |
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