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CAREER: Origins of Cellular Heterogeneity by Dynamically-linked Multiplexed Imaging — NSF Award to Duke University (NC, $574,808)

T cells are a type of white blood cell that plays an important role in the functioning of the immune system. Therapies based on T cells (CAR T-cell therapy) are proving to be effective for certain cancers. T cells are isolated from a patient’s blood and modified to express a binding protein (CAR) that allows the T-cell

Award titleCAREER: Origins of Cellular Heterogeneity by Dynamically-linked Multiplexed Imaging
Award ID2440733
AwardeeDuke University
CityDURHAM
StateNC
Amount obligated$574,808
Principal investigatorJohn Hickey
ProgramCellular & Biochem Engineering
Start date05/01/2025
AbstractT cells are a type of white blood cell that plays an important role in the functioning of the immune system. Therapies based on T cells (CAR T-cell therapy) are proving to be effective for certain cancers. T cells are isolated from a patient’s blood and modified to express a binding protein (CAR) that allows the T-cell to more effectively attach to tumor cells. Once modified, the CAR T-cells are grown to create millions of them, and then introduced into the patient, where they bind to cancer cel
SourceNSF Awards

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