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CAREER: Principles and mechanisms of robust embryonic development — NSF Award to University of Pittsburgh (PA, $1,253,324)

Embryos are masterful bioengineers, with the ability to build every organ of the body from a single fertilized egg. This process demands astonishing coordination— millions of cells taking on specialized functions in precisely the right locations— yet embryos build healthy organisms with near perfect regularity. This pr

Award titleCAREER: Principles and mechanisms of robust embryonic development
Award ID2541338
AwardeeUniversity of Pittsburgh
CityPITTSBURGH
StatePA
Amount obligated$1,253,324
Principal investigatorNathan Lord
ProgramCell, Dev, & Physio
Start date06/01/2026
AbstractEmbryos are masterful bioengineers, with the ability to build every organ of the body from a single fertilized egg. This process demands astonishing coordination— millions of cells taking on specialized functions in precisely the right locations— yet embryos build healthy organisms with near perfect regularity. This project aims to understand the origins of this reliability: how do embryos prevent, recognize and correct mistakes before they cause birth defects? The work will be broken up into th
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