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CAREER: Scalable algorithms for regularized and non-linear genetic models of gene expressi — NSF Award to University of California

DNA mutations have a profound effect on how genes work, but it’s still not well understood which mutations affect which genes. Currently, our knowledge is limited due to challenges in analyzing genomics data, such as statistical errors arising from an overrepresentation of study participants from specific groups and si

Award titleCAREER: Scalable algorithms for regularized and non-linear genetic models of gene expressi
Award ID2336469
AwardeeUniversity of California-San Diego
CityLA JOLLA
StateCA
Amount obligated$444,000
Principal investigatorTiffany Amariuta-Bartell
ProgramInfo Integration & Informatics
Start date03/01/2024
AbstractDNA mutations have a profound effect on how genes work, but it’s still not well understood which mutations affect which genes. Currently, our knowledge is limited due to challenges in analyzing genomics data, such as statistical errors arising from an overrepresentation of study participants from specific groups and simplistic statistical models that do not sufficiently capture the data. This project overcomes these challenges across three main scientific goals, in which innovative statistical m
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