CAREER: Structural Implications of Nucleic Acid Nanoparticles on their Transcription, Tran — NSF Award to Case Western Reserve Uni
Delivering therapeutic drug molecules or genes to cells requires nanoscale carriers that can interact with proteins inside the cell and navigate to the nucleus, if needed. Nanoparticles made entirely out of synthetic deoxyribonucleic acid strands have proven useful in building such delivery systems. Although they work
| Award title | CAREER: Structural Implications of Nucleic Acid Nanoparticles on their Transcription, Tran |
|---|---|
| Award ID | 2439298 |
| Awardee | Case Western Reserve University |
| City | CLEVELAND |
| State | OH |
| Amount obligated | $695,000 |
| Principal investigator | Divita Mathur |
| Program | Nanoscale Interactions Program |
| Start date | 07/01/2025 |
| Abstract | Delivering therapeutic drug molecules or genes to cells requires nanoscale carriers that can interact with proteins inside the cell and navigate to the nucleus, if needed. Nanoparticles made entirely out of synthetic deoxyribonucleic acid strands have proven useful in building such delivery systems. Although they work well for drug delivery, their behavior inside the cell is not fully understood, which presents challenges to improving nanoparticles for specific applications. This project will en |
| Source | NSF Awards |
$799/mo
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