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Collaborative Research: DMREF: GOALI: High-Affinity Supramolecular Peptide Materials for S — NSF Award to Johns Hopkins University

NON-TECHNICAL SUMMARY This project is an integrated experimental-computational approach that aims to develop a class of peptide-based supramolecular materials as high-affinity precipitants for non-chromatographic protein purification. The separation and purification of therapeutic proteins from their biological resourc

Award titleCollaborative Research: DMREF: GOALI: High-Affinity Supramolecular Peptide Materials for S
Award ID2119653
AwardeeJohns Hopkins University
CityBALTIMORE
StateMD
Amount obligated$600,000
Principal investigatorHonggang Cui
ProgramBIOMATERIALS PROGRAM, DMREF
Start date10/01/2021
AbstractNON-TECHNICAL SUMMARY This project is an integrated experimental-computational approach that aims to develop a class of peptide-based supramolecular materials as high-affinity precipitants for non-chromatographic protein purification. The separation and purification of therapeutic proteins from their biological resources are a significant limitation for industrial manufacturing of biologics in terms of their efficiency and cost-effectiveness. Despite the high media cost and limited loading capac
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