Collaborative Research: eMB: A deep learning-enhanced multiphysics and multiscale framewor — NSF Award to Yale University (CT, $10
Erythrophagocytosis is a complex multiphysics process involving recognizing, engulfing, and digesting aged or diseased red blood cells (RBCs) by phagocytic cells. Biochemical signaling pathways mediated by ligand-receptor engagement have been considered as key factors in initiating and driving the phagocytosis of abnor
| Award title | Collaborative Research: eMB: A deep learning-enhanced multiphysics and multiscale framewor |
|---|---|
| Award ID | 2527294 |
| Awardee | Yale University |
| City | NEW HAVEN |
| State | CT |
| Amount obligated | $100,000 |
| Principal investigator | Lu Lu |
| Program | MATHEMATICAL BIOLOGY |
| Start date | 09/01/2025 |
| Abstract | Erythrophagocytosis is a complex multiphysics process involving recognizing, engulfing, and digesting aged or diseased red blood cells (RBCs) by phagocytic cells. Biochemical signaling pathways mediated by ligand-receptor engagement have been considered as key factors in initiating and driving the phagocytosis of abnormal RBCs by tissue-resident macrophages in the spleen and the liver. However, growing evidence has underscored the effect of the stiffness of RBCs in modulating the engulfment proc |
| Source | NSF Awards |
$799/mo
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