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Collaborative Research: Structure and Function of Direct Delivery Peptides — NSF Award to Oregon State University (OR, $200,000)

Non-technical description Every living cell is surrounded by a very thin membrane barrier that keeps most large and water-soluble molecules out of the cell. The membrane protects the cell, but it also makes it hard to deliver useful cargo molecules, such as drugs, into cells. Short molecules called cell penetrating pep

Award titleCollaborative Research: Structure and Function of Direct Delivery Peptides
Award ID2534517
AwardeeOregon State University
CityCORVALLIS
StateOR
Amount obligated$200,000
Principal investigatorMyriam Cotten
ProgramBIOMATERIALS PROGRAM
Start date04/01/2026
AbstractNon-technical description Every living cell is surrounded by a very thin membrane barrier that keeps most large and water-soluble molecules out of the cell. The membrane protects the cell, but it also makes it hard to deliver useful cargo molecules, such as drugs, into cells. Short molecules called cell penetrating peptides can sometimes carry cargo across this barrier, but most known examples work inefficiently and tend to trap their cargo inside internal compartments where the cargo cannot do
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