Computational framework for identifiable and phase-consistent allele-specific expression q — NSF Award to University of Pittsburgh
Haplotype inference and allele-specific transcript expression quantification are two fundamental problems in genetics and genomics. Haplotype inference aligns maternal and paternal alleles of genetic variants along two diploid chromosomes, whereas allele-specific expression quantification obtains the expression levels
| Award title | Computational framework for identifiable and phase-consistent allele-specific expression q |
|---|---|
| Award ID | 2505285 |
| Awardee | University of Pittsburgh |
| City | PITTSBURGH |
| State | PA |
| Amount obligated | $595,875 |
| Principal investigator | Seyoung Kim |
| Program | Innovation: Bioinformatics |
| Start date | 10/01/2024 |
| Abstract | Haplotype inference and allele-specific transcript expression quantification are two fundamental problems in genetics and genomics. Haplotype inference aligns maternal and paternal alleles of genetic variants along two diploid chromosomes, whereas allele-specific expression quantification obtains the expression levels of transcripts of maternal and paternal origins from RNA-seq reads. These two problems are coupled in that one can affect the accuracy of the other: accurate allele-specific expres |
| Source | NSF Awards |
$799/mo
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