Cracking the codon code for pathogen effector secretion in host plant cells — NSF Award to University of Nebraska-Lincoln (NE, $76
Plant pathogens threaten global food security. During early infection, oomycetes and fungi, including the fungal rice destroyer Magnaporthe oryzae, often grow in intimate contact with living host plant cells. During this growth stage the pathogen deploys secreted proteins (effectors) to suppress host defenses. In turn,
| Award title | Cracking the codon code for pathogen effector secretion in host plant cells |
|---|---|
| Award ID | 2512144 |
| Awardee | University of Nebraska-Lincoln |
| City | LINCOLN |
| State | NE |
| Amount obligated | $769,792 |
| Principal investigator | Richard Wilson |
| Program | Plant-Biotic Interactions |
| Start date | 08/15/2025 |
| Abstract | Plant pathogens threaten global food security. During early infection, oomycetes and fungi, including the fungal rice destroyer Magnaporthe oryzae, often grow in intimate contact with living host plant cells. During this growth stage the pathogen deploys secreted proteins (effectors) to suppress host defenses. In turn, the plant can recognize these effectors via intracellular resistance (R) proteins to trigger immunity. However, pathogens can lose or rapidly alter effectors to enable host jumps |
| Source | NSF Awards |
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