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Cytoskeletal regulation of single cell migration in complex environments — NSF Award to Columbia University (NY, $1,132,274)

This project will provide significant new information about how single cells are able to squeeze through tight spaces, by understanding how the scaffolds that support cell shape are remodeled and coordinated. Cells come in all shapes and sizes and often need to move through constricted spaces to perform their functions

Award titleCytoskeletal regulation of single cell migration in complex environments
Award ID2517807
AwardeeColumbia University
CityNEW YORK
StateNY
Amount obligated$1,132,274
Principal investigatorEmily Mace
ProgramCellular Dynamics and Function
Start date09/01/2025
AbstractThis project will provide significant new information about how single cells are able to squeeze through tight spaces, by understanding how the scaffolds that support cell shape are remodeled and coordinated. Cells come in all shapes and sizes and often need to move through constricted spaces to perform their functions. The mechanisms that allow small cells to move quickly and nimbly can be conserved between different organisms, from the smallest nematode worms to humans. Specifically, this proj
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