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Designing DNA Origami for Force-mediated Release of Molecular Cargo — NSF Award to Iowa State University (IA, $552,075)

This award to Iowa State University is supporting research that will design, build and test a nanosized container made using a technique called DNA origami. This nanosized container can release molecules in response to small forces exerted within tissues. Forces play an important role in biology. During tissue developm

Award titleDesigning DNA Origami for Force-mediated Release of Molecular Cargo
Award ID2333556
AwardeeIowa State University
CityAMES
StateIA
Amount obligated$552,075
Principal investigatorIan Schneider
ProgramEngineering of Biomed Systems, BMMB-Biomech & Mechanobiology, BIOSENS-Biosensing
Start date07/01/2024
AbstractThis award to Iowa State University is supporting research that will design, build and test a nanosized container made using a technique called DNA origami. This nanosized container can release molecules in response to small forces exerted within tissues. Forces play an important role in biology. During tissue development and disease, cells exert forces on the extracellular matrix (ECM), the protein web that surrounds cells. These forces both create tissue structure and communicate information t
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