Divergent binder engineering through multi-pathway protein display — NSF Award to University of Connecticut (CT, $427,467)
Proteins often target specific areas in the cell. Some reside exclusively inside the cell, some embed themselves in the cell wall, and some are tethered to the outside of the cell. Others are actively secreted. Designing therapeutic drugs or proteins must account for the location of the target protein. Many important t
| Award title | Divergent binder engineering through multi-pathway protein display |
|---|---|
| Award ID | 2600254 |
| Awardee | University of Connecticut |
| City | STORRS |
| State | CT |
| Amount obligated | $427,467 |
| Principal investigator | Yongku Cho |
| Program | Cellular & Biochem Engineering |
| Start date | 05/01/2026 |
| Abstract | Proteins often target specific areas in the cell. Some reside exclusively inside the cell, some embed themselves in the cell wall, and some are tethered to the outside of the cell. Others are actively secreted. Designing therapeutic drugs or proteins must account for the location of the target protein. Many important targets, like viral proteins, are initially inside the cell. Developing proteins that can specifically recognize and bind to them inside a cell is challenging. The cell interior pre |
| Source | NSF Awards |
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