DMS/NIGMS 1: Decoding RNA splicing dynamics from static images using mechanistic stochasti — NSF Award to University of California
This project investigates splicing, a fundamental cellular process where RNA molecules from the same gene are processed to produce multiple distinct proteins. This flexibility is essential for healthy development, and splicing errors are linked to numerous human diseases, including cancer and neurodegenerative disorder
| Award title | DMS/NIGMS 1: Decoding RNA splicing dynamics from static images using mechanistic stochasti |
|---|---|
| Award ID | 2451263 |
| Awardee | University of California-Irvine |
| City | IRVINE |
| State | CA |
| Amount obligated | $500,000 |
| Principal investigator | Fangyuan Ding |
| Program | NIGMS |
| Start date | 08/01/2025 |
| Abstract | This project investigates splicing, a fundamental cellular process where RNA molecules from the same gene are processed to produce multiple distinct proteins. This flexibility is essential for healthy development, and splicing errors are linked to numerous human diseases, including cancer and neurodegenerative disorders. A major obstacle in understanding splicing control is that traditional live-cell imaging interferes with the very dynamics under observation. This research overcomes this limita |
| Source | NSF Awards |
$799/mo
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