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DMS/NIGMS 1: Developing a mathematical framework to understand viral-cellular transduction — NSF Award to North Carolina State Uni

Genetically engineered cell therapies are transforming how doctors treat challenging diseases like cancer, sickle cell disease, HIV, and autoimmune conditions. These treatments work by giving a patient’s own cells a new ability to find and fight disease more effectively. A crucial step in making these cell therapies ac

Award titleDMS/NIGMS 1: Developing a mathematical framework to understand viral-cellular transduction
Award ID2451660
AwardeeNorth Carolina State University
CityRALEIGH
StateNC
Amount obligated$500,000
Principal investigatorAndrey Kuznetsov
ProgramNIGMS
Start date09/01/2025
AbstractGenetically engineered cell therapies are transforming how doctors treat challenging diseases like cancer, sickle cell disease, HIV, and autoimmune conditions. These treatments work by giving a patient’s own cells a new ability to find and fight disease more effectively. A crucial step in making these cell therapies accessible is by swiftly delivering new genetic material into cells using viral vectors in a liquid medium. Porous materials that guide the flow of cells and viruses dramatically imp
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