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DREAM Sentinels: Selection of aptamers that target viral variants with high specificity — NSF Award to University of Texas at Aust

To combat infectious diseases, this project will develop a versatile platform that has a much shorter turn-around time in generating a new capture molecule that specifically binds a new viral variant with high affinity. The investigators will further convert the captured molecule into a sensor for virus detection, and

Award titleDREAM Sentinels: Selection of aptamers that target viral variants with high specificity
Award ID2235455
AwardeeUniversity of Texas at Austin
CityAUSTIN
StateTX
Amount obligated$718,956
Principal investigatorHsin-Chih Yeh
ProgramSpecial Initiatives, BIOSENS-Biosensing, Systems and Synthetic Biology
Start date01/01/2023
AbstractTo combat infectious diseases, this project will develop a versatile platform that has a much shorter turn-around time in generating a new capture molecule that specifically binds a new viral variant with high affinity. The investigators will further convert the captured molecule into a sensor for virus detection, and also turn it into a blocking molecule to neutralize the virus. The current selection process is time-consuming and labor intensive. The goal of this project is to develop a streaml
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