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EAGER: Computationally Predicting and Characterizing the Immune Response to Viral Infectio — NSF Award to University of Minnesota-

Pathogens such as the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) affect different people differently. Whether an individual mounts a strong response or not depends, at least in part, on their genes. Specific genes code for the proteins on the surface of cells that present viral protein fragments to th

Award titleEAGER: Computationally Predicting and Characterizing the Immune Response to Viral Infectio
Award ID2036064
AwardeeUniversity of Minnesota-Twin Cities
CityMINNEAPOLIS
StateMN
Amount obligated$200,000
Principal investigatorMarc Riedel
ProgramFET-Fndtns of Emerging Tech
Start date08/01/2020
AbstractPathogens such as the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) affect different people differently. Whether an individual mounts a strong response or not depends, at least in part, on their genes. Specific genes code for the proteins on the surface of cells that present viral protein fragments to the immune system. Killer T cells recognize these fragments and kill the infected cells. The immune response to SARS-CoV-2 hinges on whether the viral protein fragments bind into a g
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