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EAGER: Decoding Maize Transcription Factor-Mediator Interactions: A Breakthrough Tool for — NSF Award to Michigan State University

The translation of genotype into phenotype relies on tightly regulated gene expression, orchestrated by transcription factors (TFs) tethered to cis-regulatory elements and interacting with the multi-subunit Mediator (MED) complex, which plays a crucial role in conveying regulatory information from TFs to the transcript

Award titleEAGER: Decoding Maize Transcription Factor-Mediator Interactions: A Breakthrough Tool for
Award ID2539770
AwardeeMichigan State University
CityEAST LANSING
StateMI
Amount obligated$299,466
Principal investigatorErich Grotewold
ProgramPlant Genome Research Resource
Start date11/01/2025
AbstractThe translation of genotype into phenotype relies on tightly regulated gene expression, orchestrated by transcription factors (TFs) tethered to cis-regulatory elements and interacting with the multi-subunit Mediator (MED) complex, which plays a crucial role in conveying regulatory information from TFs to the transcriptional machinery. TFs have been widely utilized to manipulate plant metabolism, stress responses, and developmental processes; however, unintended regulatory activities have often l
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