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EDGE FGT: New approaches to rapidly domesticate non-model Clostridia for applications in s — NSF Award to Northeastern University

The Clostridia are a diverse group of bacteria that range from agents of human disease to industrial microbes used for renewable production of biofuels and biochemicals. Despite the importance of these bacteria, the majority cannot be genetically engineered, and even those that can are notoriously difficult to work wit

Award titleEDGE FGT: New approaches to rapidly domesticate non-model Clostridia for applications in s
Award ID2421566
AwardeeNortheastern University
CityBOSTON
StateMA
Amount obligated$1,271,828
Principal investigatorBenjamin Woolston
ProgramEDGE Tools
Start date09/01/2024
AbstractThe Clostridia are a diverse group of bacteria that range from agents of human disease to industrial microbes used for renewable production of biofuels and biochemicals. Despite the importance of these bacteria, the majority cannot be genetically engineered, and even those that can are notoriously difficult to work with. This project develops fundamentally new approaches for genetically manipulating these bacteria, allowing scientists to study and control their unique physiology and metabolism a
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