EDGE FGT: Universal viral-based systems to accelerate gene editing research across the tax — NSF Award to Pennsylvania State Univ
Genetic manipulation is usually performed by injecting gene editing materials into embryos, which is difficult, expensive, and inefficient. We have identified a virus that infects the ovaries and testes of arthropods after injecting them or feeding it to them. When the virus is modified to carry gene editing materials,
| Award title | EDGE FGT: Universal viral-based systems to accelerate gene editing research across the tax |
|---|---|
| Award ID | 2525447 |
| Awardee | Pennsylvania State Univ University Park |
| City | UNIVERSITY PARK |
| State | PA |
| Amount obligated | $2,200,000 |
| Principal investigator | Jason Rasgon |
| Program | EDGE Tools |
| Start date | 11/01/2025 |
| Abstract | Genetic manipulation is usually performed by injecting gene editing materials into embryos, which is difficult, expensive, and inefficient. We have identified a virus that infects the ovaries and testes of arthropods after injecting them or feeding it to them. When the virus is modified to carry gene editing materials, infected arthropods have genetically modified offspring, a technique that is much easier than traditional methods. We call this method “Germline Engineering by Viral Transduction” |
| Source | NSF Awards |
$799/mo
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