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Elucidating principles of microbiome spatial organization using synthetic gut communities — NSF Award to Columbia University (NY,

The human digestive tract contains complex communities of microbes that contribute to human health by facilitating nutrient metabolism and digestion, promoting immune function, and providing protection against pathogens. To provide these human health benefits, microbial communities must be able to colonize and persist

Award titleElucidating principles of microbiome spatial organization using synthetic gut communities
Award ID2522218
AwardeeColumbia University
CityNEW YORK
StateNY
Amount obligated$914,479
Principal investigatorHarris Wang
ProgramSystems and Synthetic Biology
Start date09/01/2025
AbstractThe human digestive tract contains complex communities of microbes that contribute to human health by facilitating nutrient metabolism and digestion, promoting immune function, and providing protection against pathogens. To provide these human health benefits, microbial communities must be able to colonize and persist in the human digestive tract. This project will analyze several factors that are important for assembly and stability of these communities, and will provide tools that the scientif
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