Engineering biosynthesis and incorporation of an immunogenic amino acid — NSF Award to University of Delaware (DE, $329,000)
Live bacterial vaccines can be engineered to more effectively trigger a desired immune response to prevent infection. This project examines an approach to making more effective live bacterial vaccines by engineering the bacteria to introduce certain atypical protein building blocks, called non-native amino acids (NNAAs
| Award title | Engineering biosynthesis and incorporation of an immunogenic amino acid |
|---|---|
| Award ID | 2032243 |
| Awardee | University of Delaware |
| City | NEWARK |
| State | DE |
| Amount obligated | $329,000 |
| Principal investigator | Aditya Kunjapur |
| Program | Cellular & Biochem Engineering |
| Start date | 01/01/2021 |
| Abstract | Live bacterial vaccines can be engineered to more effectively trigger a desired immune response to prevent infection. This project examines an approach to making more effective live bacterial vaccines by engineering the bacteria to introduce certain atypical protein building blocks, called non-native amino acids (NNAAs), into their proteins. These NNAAs could help stimulate an immune response against proteins in bacteria that would usually evade the immune response, thus leading to more effectiv |
| Source | NSF Awards |
$799/mo
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