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Fast and Robust Algorithms in Cryo-Electron Microscopy Imaging — NSF Award to University of California-Davis (CA, $250,000)

Cryo-electron microscopy (cryo-EM) has revolutionized the way scientists uncover the 3D structure of proteins, making critical contributions to our understanding of viruses, cancer, and neurodegenerative diseases. However, despite its transformative potential, cryo-EM is limited by the immense computational cost requir

Award titleFast and Robust Algorithms in Cryo-Electron Microscopy Imaging
Award ID2514152
AwardeeUniversity of California-Davis
CityDAVIS
StateCA
Amount obligated$250,000
Principal investigatorYunpeng Shi
ProgramCOMPUTATIONAL MATHEMATICS
Start date09/01/2025
AbstractCryo-electron microscopy (cryo-EM) has revolutionized the way scientists uncover the 3D structure of proteins, making critical contributions to our understanding of viruses, cancer, and neurodegenerative diseases. However, despite its transformative potential, cryo-EM is limited by the immense computational cost required to process the large, noisy, and unstructured image data it generates. This project aims to overcome these barriers by developing robust, efficient, and theoretically guaranteed
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