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Fluidic Protein Vesicles for High-Density Signal Presentation in Immunomodulatory Biomater — NSF Award to University of Florida (F

PART 1: NON-TECHNICAL SUMMARY Living cells constantly communicate and respond to their surroundings using complex molecular interactions on their surfaces. Many life-saving immunotherapies, such as engineered T cells used to fight cancer, rely on these surface interactions to activate the immune system. However, buildi

Award titleFluidic Protein Vesicles for High-Density Signal Presentation in Immunomodulatory Biomater
Award ID2532798
AwardeeUniversity of Florida
CityGAINESVILLE
StateFL
Amount obligated$507,298
Principal investigatorYeongseon Jang
ProgramBIOMATERIALS PROGRAM
Start date01/01/2026
AbstractPART 1: NON-TECHNICAL SUMMARY Living cells constantly communicate and respond to their surroundings using complex molecular interactions on their surfaces. Many life-saving immunotherapies, such as engineered T cells used to fight cancer, rely on these surface interactions to activate the immune system. However, building artificial systems that can reliably mimic these natural signals has been very difficult. Current synthetic materials cannot easily control how proteins cluster, move, and organ
SourceNSF Awards

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