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Hypothesis-based interpretability for high-dimensional models of T cell signaling — NSF Award to University of California-Irvine (

Living cells receive signals from other cells and process this information to make decisions and take actions. One example is provided by immune cells processing information about other cells to decide whether to mount an immune response. Decades of mathematics have revealed how parts of this information processing sys

Award titleHypothesis-based interpretability for high-dimensional models of T cell signaling
Award ID2602179
AwardeeUniversity of California-Irvine
CityIRVINE
StateCA
Amount obligated$465,777
Principal investigatorJun Allard
ProgramMATHEMATICAL BIOLOGY
Start date07/01/2026
AbstractLiving cells receive signals from other cells and process this information to make decisions and take actions. One example is provided by immune cells processing information about other cells to decide whether to mount an immune response. Decades of mathematics have revealed how parts of this information processing system work, but the insights were limited by the mathematical technology of the time. Recent artificial intelligence and machine learning methods have powerful abilities to predict h
SourceNSF Awards

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