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LOCK-AND-KEY INTERACTIONS BETWEEN CHIRAL NANOPARTICLES AND PROTEINS — NSF Award to Regents of the University of Michigan - Ann Arb

Ultrasmall particles with nanoscale dimensions, often referred to as nanoparticles, are potent new agents for treatment of cancers, preservation of vaccines and inhibition of harmful otherwise untreatable bacterial infections. The geometric shape of the nanoparticles plays a significant role in their medical efficacy b

Award titleLOCK-AND-KEY INTERACTIONS BETWEEN CHIRAL NANOPARTICLES AND PROTEINS
Award ID2317423
AwardeeRegents of the University of Michigan - Ann Arbor
CityANN ARBOR
StateMI
Amount obligated$457,613
Principal investigatorNicholas Kotov
ProgramNanoscale Interactions Program
Start date07/01/2023
AbstractUltrasmall particles with nanoscale dimensions, often referred to as nanoparticles, are potent new agents for treatment of cancers, preservation of vaccines and inhibition of harmful otherwise untreatable bacterial infections. The geometric shape of the nanoparticles plays a significant role in their medical efficacy but understanding how to make particles with complex shapes, which serve the patients well, is also critical. This project will extend the concept of lock-and-key interactions betwe
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