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NSF-ANR MCB/PHY: DNA Origami-based machines for epigenetic manipulation of gene transcript — NSF Award to OHIO STATE UNIVERSITY, T

All cell types must precisely express the correct sets of genes, in order to properly use the information encoded in chromosomal DNA for their distinct functions. The ability to target, detect, and control the use of the genetic information on a single cell basis can provide crucial fundamental insights and the ability

Award titleNSF-ANR MCB/PHY: DNA Origami-based machines for epigenetic manipulation of gene transcript
Award ID2411725
AwardeeOHIO STATE UNIVERSITY, THE
CityCOLUMBUS
StateOH
Amount obligated$700,000
Principal investigatorMichael Poirier
ProgramGenetic Mechanisms, PHYSICS OF LIVING SYSTEMS
Start date06/01/2024
AbstractAll cell types must precisely express the correct sets of genes, in order to properly use the information encoded in chromosomal DNA for their distinct functions. The ability to target, detect, and control the use of the genetic information on a single cell basis can provide crucial fundamental insights and the ability to influence how genes function and are regulated. This project will develop and implement multifunctional DNA-based nanoscale devices to detect genetic activity and even control
SourceNSF Awards

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