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NSF/BIO-UKRI/BBSRC: Computational Proteomics in a New Physical Dimension — NSF Award to University of California-San Diego (CA, $1

Determining the sequence of amino acids in a peptide—peptide sequencing—is a foundational technique in drug discovery, food safety, and environmental monitoring. This project aims to enable confident identification of challenging classes of peptides for which current state-of-the-art methods fail or produce unreliable

Award titleNSF/BIO-UKRI/BBSRC: Computational Proteomics in a New Physical Dimension
Award ID2526602
AwardeeUniversity of California-San Diego
CityLA JOLLA
StateCA
Amount obligated$1,200,000
Principal investigatorPavel Pevzner
ProgramInnovation: Bioinformatics
Start date11/01/2025
AbstractDetermining the sequence of amino acids in a peptide—peptide sequencing—is a foundational technique in drug discovery, food safety, and environmental monitoring. This project aims to enable confident identification of challenging classes of peptides for which current state-of-the-art methods fail or produce unreliable results. Today’s dominant technology for peptide identification is mass spectrometry (MS), which performs well when peptides match sequences in a reference database. However, MS st
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