NSF-SNSF: Programmable and dynamically-responsive bacterial therapeutics for cancer immuno — NSF Award to University of Washington
Living cells can act as programmable and dynamically-responsive therapeutics to treat cancer. Although engineered human T cells have been effective for cancer therapy, they are almost prohibitively expensive. In contrast, bacterial cells can be manufactured at low cost and therefore hold promise as broadly applicable t
| Award title | NSF-SNSF: Programmable and dynamically-responsive bacterial therapeutics for cancer immuno |
|---|---|
| Award ID | 2516785 |
| Awardee | University of Washington |
| City | SEATTLE |
| State | WA |
| Amount obligated | $353,843 |
| Principal investigator | Jesse Zalatan |
| Program | BIOSENS-Biosensing |
| Start date | 03/01/2025 |
| Abstract | Living cells can act as programmable and dynamically-responsive therapeutics to treat cancer. Although engineered human T cells have been effective for cancer therapy, they are almost prohibitively expensive. In contrast, bacterial cells can be manufactured at low cost and therefore hold promise as broadly applicable therapeutics. To enable effective live-cell bacterial therapeutics, this project will develop a unique biosensing system to detect specific tumor antigens and respond with potent th |
| Source | NSF Awards |
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