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OPP-PRF: Genetic Mechanisms of Renal Adaptations and Antifreeze-Induced Kidney Plasticity — NSF Award to University of Houston (TX

Water temperatures in the polar oceans can drop below the freezing point of animal tissues, resulting in the formation of ice crystals that can cause potentially fatal tissue damage. To survive in the frozen polar oceans, some fish species produce antifreeze proteins, which suppress the formation of ice crystals. These

Award titleOPP-PRF: Genetic Mechanisms of Renal Adaptations and Antifreeze-Induced Kidney Plasticity
Award ID2420167
AwardeeUniversity of Houston
CityHOUSTON
StateTX
Amount obligated$323,227
Principal investigatorDaniel Wright
ProgramANT Organisms & Ecosystems
Start date09/01/2024
AbstractWater temperatures in the polar oceans can drop below the freezing point of animal tissues, resulting in the formation of ice crystals that can cause potentially fatal tissue damage. To survive in the frozen polar oceans, some fish species produce antifreeze proteins, which suppress the formation of ice crystals. These proteins must be maintained at high concentrations in the blood to be effective, but they are small enough to be filtered by the kidney and lost in urine. Their active re-absorpti
SourceNSF Awards

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