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RAISE: T4C: Reprogramming cellular signaling pathways with implanted integrated circuits — NSF Award to University of California-S

Cells contain complex networks of proteins that interact with each other in much the same way that electronic components interact in a circuit. Understanding how these circuits work has been a major goal in cell biology. Most tools available to researchers involve breaking molecular circuits, for example by removing on

Award titleRAISE: T4C: Reprogramming cellular signaling pathways with implanted integrated circuits
Award ID2434588
AwardeeUniversity of California-San Francisco
CitySAN FRANCISCO
StateCA
Amount obligated$439,999
Principal investigatorWallace Marshall
ProgramCSCS: Circuits and Systems for, Cross-BIO Activities, Cellular Dynamics and Function, Systems and Synthetic Biology
Start date03/01/2025
AbstractCells contain complex networks of proteins that interact with each other in much the same way that electronic components interact in a circuit. Understanding how these circuits work has been a major goal in cell biology. Most tools available to researchers involve breaking molecular circuits, for example by removing one or more of the proteins in the network. This project will develop a method for adding new connections to the networks inside a cell, by implanting a physical electronic device th
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