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RAPID: Structure, Function and Dynamics of SARS Coronavirus-2 Main Protease 3CLpro Determi — NSF Award to University of Wisconsin-

An award is made to the University of Wisconsin-Milwaukee (UWM) to investigate the molecular mechanism of an essential coronavirus protease reaction in real time. This project addresses fundamental questions how the SARS coronavirus-2 (CoV-2) proliferates. CoV-2 is the source of the worldwide COVID-19 pandemic, which s

Award titleRAPID: Structure, Function and Dynamics of SARS Coronavirus-2 Main Protease 3CLpro Determi
Award ID2030466
AwardeeUniversity of Wisconsin-Milwaukee
CityMILWAUKEE
StateWI
Amount obligated$199,566
Principal investigatorMarius Schmidt
ProgramCOVID-19 Research
Start date07/01/2020
AbstractAn award is made to the University of Wisconsin-Milwaukee (UWM) to investigate the molecular mechanism of an essential coronavirus protease reaction in real time. This project addresses fundamental questions how the SARS coronavirus-2 (CoV-2) proliferates. CoV-2 is the source of the worldwide COVID-19 pandemic, which severely impacts public health and national prosperity. The CoV-2 main protease, also called 3CLpro, catalyzes an essential reaction for assembly of CoV-2 infectious particles. If t
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