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Role of Aging and Diabetes Related Changes to the Extracellular Matrix on Cancer Invasion — NSF Award to New Jersey Institute of T

Cancer becomes life-threatening when tumor cells spread from the original tumor to other parts of the body. This spreading process depends not only on the cancer cells themselves, but also on the surrounding tissue called the extracellular matrix (ECM). The ECM provides physical support to cells. The structure and mech

Award titleRole of Aging and Diabetes Related Changes to the Extracellular Matrix on Cancer Invasion
Award ID2529738
AwardeeNew Jersey Institute of Technology
CityNEWARK
StateNJ
Amount obligated$529,945
Principal investigatorFarid Alisafaei
ProgramEngineering of Biomed Systems, BMMB-Biomech & Mechanobiology
Start date07/01/2026
AbstractCancer becomes life-threatening when tumor cells spread from the original tumor to other parts of the body. This spreading process depends not only on the cancer cells themselves, but also on the surrounding tissue called the extracellular matrix (ECM). The ECM provides physical support to cells. The structure and mechanical properties of ECM change with age and with diseases such as diabetes. These changes in ECM may make it easier for tumor cells to spread into healthy tissue, but the underlyi
SourceNSF Awards

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