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RUI: BIOPOLYMER - BIObricks POLYketide Metabolic EngineeRing platform — NSF Award to Ferris State University (Inc.) (MI, $407,901)

Soil bacteria make compounds called anthracyclinones (ACs), some of which have powerful therapeutic activity. ACs have complicated structures that are produced by enzymes found in the bacteria. This project will “mix-and-match” these enzymes to make novel ACs expected to have antibiotic and anticancer activity. As a Re

Award titleRUI: BIOPOLYMER - BIObricks POLYketide Metabolic EngineeRing platform
Award ID2015951
AwardeeFerris State University (Inc.)
CityBIG RAPIDS
StateMI
Amount obligated$407,901
Principal investigatorStephen Nybo
ProgramCellular & Biochem Engineering
Start date07/01/2020
AbstractSoil bacteria make compounds called anthracyclinones (ACs), some of which have powerful therapeutic activity. ACs have complicated structures that are produced by enzymes found in the bacteria. This project will “mix-and-match” these enzymes to make novel ACs expected to have antibiotic and anticancer activity. As a Research in Undergraduate Institutions (RUI) project, it will attract undergraduate students to careers in science and engineering by involving them in the completion of the research
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