RUI: BMAT: Evaluating Ionizable Amphiphilic Janus Dendrimers as Delivery Agents for Nuclei — NSF Award to Ursinus College (PA, $23
NON-TECHNICAL SUMMARY: Methods to alter gene expression have the potential to transform modern medicine. These tools directly modify genetic information or change how much or how little a specific gene is expressed. Many of these approaches use molecules called nucleic acids to treat disease, but for these therapies to
| Award title | RUI: BMAT: Evaluating Ionizable Amphiphilic Janus Dendrimers as Delivery Agents for Nuclei |
|---|---|
| Award ID | 2447992 |
| Awardee | Ursinus College |
| City | COLLEGEVILLE |
| State | PA |
| Amount obligated | $230,784 |
| Principal investigator | Samantha Wilner |
| Program | BIOMATERIALS PROGRAM |
| Start date | 08/01/2025 |
| Abstract | NON-TECHNICAL SUMMARY: Methods to alter gene expression have the potential to transform modern medicine. These tools directly modify genetic information or change how much or how little a specific gene is expressed. Many of these approaches use molecules called nucleic acids to treat disease, but for these therapies to be successful, small particles or vesicles must encapsulate and carry these nucleic acids to desired cell types. Various biomaterials such as lipids, polymers, and dendrimers have |
| Source | NSF Awards |
$799/mo
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