RUI: Exploring the Utility of Antiparallel Triplex-forming CNA Dimers as Sequence-specific — NSF Award to The University Corporati
With this award, the Chemistry of Life Processes Program in the Chemistry Division is funding Dr. Thomas Minehan from California State University, Northridge to design and synthesize hybrid molecules that can recognize DNA sequences. Nucleic acid-like bases are attached to a protein-like (carbamate) polymer to create c
| Award title | RUI: Exploring the Utility of Antiparallel Triplex-forming CNA Dimers as Sequence-specific |
|---|---|
| Award ID | 2506192 |
| Awardee | The University Corporation, Northridge |
| City | NORTHRIDGE |
| State | CA |
| Amount obligated | $345,248 |
| Principal investigator | Thomas Minehan |
| Program | Chemistry of Life Processes |
| Start date | 09/01/2025 |
| Abstract | With this award, the Chemistry of Life Processes Program in the Chemistry Division is funding Dr. Thomas Minehan from California State University, Northridge to design and synthesize hybrid molecules that can recognize DNA sequences. Nucleic acid-like bases are attached to a protein-like (carbamate) polymer to create carbamate nucleic acid (CNA) hybrid molecules that can recognize the sequences of double-stranded DNA. Large dye molecules are added to one end of the CNAs to distinguish DNA from R |
| Source | NSF Awards |
$799/mo
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