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Salmonella sRNAs drive the decision between active stress resistance and persister cell do — NSF Award to University of South Alab

Bacterial persister cells are relatively inactive metabolically, able to cope with long-term environmental stress and are relatively tolerant of antibiotics. This project aims to study the processes that lead to persister cell formation, as a better understanding of these processes could significantly improve our abili

Award titleSalmonella sRNAs drive the decision between active stress resistance and persister cell do
Award ID2219900
AwardeeUniversity of South Alabama
CityMOBILE
StateAL
Amount obligated$998,655
Principal investigatorGlen Borchert
ProgramSystems and Synthetic Biology, Cross-BIO Activities
Start date08/15/2022
AbstractBacterial persister cells are relatively inactive metabolically, able to cope with long-term environmental stress and are relatively tolerant of antibiotics. This project aims to study the processes that lead to persister cell formation, as a better understanding of these processes could significantly improve our ability to address societal challenges such as antibiotic resistance, foodborne illness outbreaks, and agricultural diseases. In addition, this project provides interdisciplinary studen
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