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SBIR Phase I: Development of a Novel Platform for Cost-Efficient mRNA Production in Yeast — NSF Award to CISTERNA BIOLOGICS, INC.

The broader impact of this Small Business Innovation Research (SBIR) Phase I project is to develop a platform technology that manufactures high-quality messenger RNA (mRNA) at 1/10th the cost of current systems. In Vitro Transcription (IVT), the primary method of synthesizing mRNA for therapeutics and vaccines, encount

Award titleSBIR Phase I: Development of a Novel Platform for Cost-Efficient mRNA Production in Yeast
Award ID2415711
AwardeeCISTERNA BIOLOGICS, INC.
CityOCEANSIDE
StateCA
Amount obligated$274,980
Principal investigatorHari Bhaskaran
ProgramSBIR Phase I
Start date08/15/2024
AbstractThe broader impact of this Small Business Innovation Research (SBIR) Phase I project is to develop a platform technology that manufactures high-quality messenger RNA (mRNA) at 1/10th the cost of current systems. In Vitro Transcription (IVT), the primary method of synthesizing mRNA for therapeutics and vaccines, encounters significant challenges in the form of expensive patented raw materials, complex purification processes, and supply chain shortages. There is an urgent need to fundamentally red
SourceNSF Awards

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