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Sterically-Modulated Affinity by RNA Triggers (SMART): a novel toolbox for the purificatio — NSF Award to North Carolina State Uni

CRISPR is a new gene-editing technology that is revolutionizing medicine, agriculture, and biotechnology. CRISPR offers hope for treating genetic diseases and creating improved crops and foods. These applications require manufacturing the protein complexes needed for CRISPR at high purity and large scale. This project

Award titleSterically-Modulated Affinity by RNA Triggers (SMART): a novel toolbox for the purificatio
Award ID2449235
AwardeeNorth Carolina State University
CityRALEIGH
StateNC
Amount obligated$615,550
Principal investigatorStefano Menegatti
ProgramInterfacial Engineering Progra
Start date08/01/2025
AbstractCRISPR is a new gene-editing technology that is revolutionizing medicine, agriculture, and biotechnology. CRISPR offers hope for treating genetic diseases and creating improved crops and foods. These applications require manufacturing the protein complexes needed for CRISPR at high purity and large scale. This project will develop an innovative technology to purify these enzyme complexes. The research team will create a purification toolkit that can efficiently separate and collect only the most
SourceNSF Awards

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