The spatial-temporal orchestration of Start in budding yeast — NSF Award to Rensselaer Polytechnic Institute (NY, $370,000)
Cells must balance growth against division in order to achieve the appropriate size and ensure maximal fitness in changing environments. Deregulation of size control leads to loss of fitness in lower eukaryotes such as budding yeast, and diseases such as cancer, diabetes or cardiac hypertrophy in humans. Cell size in t
| Award title | The spatial-temporal orchestration of Start in budding yeast |
|---|---|
| Award ID | 2412286 |
| Awardee | Rensselaer Polytechnic Institute |
| City | TROY |
| State | NY |
| Amount obligated | $370,000 |
| Principal investigator | Catherine Royer |
| Program | PHYSICS OF LIVING SYSTEMS |
| Start date | 09/01/2024 |
| Abstract | Cells must balance growth against division in order to achieve the appropriate size and ensure maximal fitness in changing environments. Deregulation of size control leads to loss of fitness in lower eukaryotes such as budding yeast, and diseases such as cancer, diabetes or cardiac hypertrophy in humans. Cell size in the single celled eukaryote, budding yeast, is determined at the transition from the G1 phase to the S phase of the cell cycle, called Start, driven by the expression of ~200 genes |
| Source | NSF Awards |
$799/mo
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