Theory and Computationally Guided Molecular Recognition Design for Single-Cell Population — NSF Award to Massachusetts Institute o
Antibodies in the human immune system recognize and grab specific molecules by changing their molecular structure to present a lock-and-key site tailored for the target. If this could be duplicated in sensors and medical assays, it could lead to new types of medical and environmental tests for human benefit. This proje
| Award title | Theory and Computationally Guided Molecular Recognition Design for Single-Cell Population |
|---|---|
| Award ID | 2521876 |
| Awardee | Massachusetts Institute of Technology |
| City | CAMBRIDGE |
| State | MA |
| Amount obligated | $450,000 |
| Principal investigator | Michael Strano |
| Program | BIOSENS-Biosensing |
| Start date | 08/01/2025 |
| Abstract | Antibodies in the human immune system recognize and grab specific molecules by changing their molecular structure to present a lock-and-key site tailored for the target. If this could be duplicated in sensors and medical assays, it could lead to new types of medical and environmental tests for human benefit. This project will study how the structures of synthetic molecules, adsorbed on the surface of a sensing nanoparticle to form what is called a corona, can be changed to grab onto specific mol |
| Source | NSF Awards |
$799/mo
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