Tools4Cells: Development of self-amplifying RNA systems for bacterial protein synthesis — NSF Award to William Marsh Rice Universi
An award is made to William Marsh Rice University to enable the development of a safe, programmable RNA-based system for transient protein production in bacteria. Harnessing the replicative machinery of single-stranded RNA bacteriophages and incorporating regulatory control elements, this project will produce self-repl
| Award title | Tools4Cells: Development of self-amplifying RNA systems for bacterial protein synthesis |
|---|---|
| Award ID | 2446451 |
| Awardee | William Marsh Rice University |
| City | HOUSTON |
| State | TX |
| Amount obligated | $986,944 |
| Principal investigator | Pedro Alvarez |
| Program | Innovation: Research Methods |
| Start date | 09/01/2025 |
| Abstract | An award is made to William Marsh Rice University to enable the development of a safe, programmable RNA-based system for transient protein production in bacteria. Harnessing the replicative machinery of single-stranded RNA bacteriophages and incorporating regulatory control elements, this project will produce self-replicating RNA (srRNA) scaffolds that function across a broad range of bacterial species. This platform enables precise, short-term protein production without the risks of horizontal |
| Source | NSF Awards |
$799/mo
Try NSFGrants →