Understanding How Microstructure and Interstitial Fluid Pressure Gradient Modulate Cell In — NSF Award to New Jersey Institute of
This project will study how the matrix (the mixture of proteins and other molecules that surrounds cells and provides structural and biochemical support to tissues) and the surrounding interstitial (between the spaces) fluid pressure can impact cancer cells within a biomimetic (biology imitating) model. The chemical an
| Award title | Understanding How Microstructure and Interstitial Fluid Pressure Gradient Modulate Cell In |
|---|---|
| Award ID | 2426919 |
| Awardee | New Jersey Institute of Technology |
| City | NEWARK |
| State | NJ |
| Amount obligated | $575,000 |
| Principal investigator | Amir Miri |
| Program | Engineering of Biomed Systems |
| Start date | 12/01/2024 |
| Abstract | This project will study how the matrix (the mixture of proteins and other molecules that surrounds cells and provides structural and biochemical support to tissues) and the surrounding interstitial (between the spaces) fluid pressure can impact cancer cells within a biomimetic (biology imitating) model. The chemical and physical signals lead to cancer cells invading nearby tissue. A well-known physical signal is interstitial fluid pressure, and biomimetic pressure modeling can improve the curren |
| Source | NSF Awards |
$799/mo
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