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Using optogenetics to characterize signal propagation and control within gene regulatory n — NSF Award to Trustees of Boston Unive

Biological systems use complex networks of sensors and regulatory pathways to respond to and change their surrounding environments. In recent years, synthetic biologists strived to modify and repurpose these networks to change what organisms can do, and to use the modified or synthetic organisms for biotechnology, biom

Award titleUsing optogenetics to characterize signal propagation and control within gene regulatory n
Award ID2533553
AwardeeTrustees of Boston University
CityBOSTON
StateMA
Amount obligated$885,642
Principal investigatorMary Dunlop
ProgramSystems and Synthetic Biology
Start date09/01/2025
AbstractBiological systems use complex networks of sensors and regulatory pathways to respond to and change their surrounding environments. In recent years, synthetic biologists strived to modify and repurpose these networks to change what organisms can do, and to use the modified or synthetic organisms for biotechnology, biomedicine and agriculture applications. However, our lack of knowledge about network function and organization often made it difficult to rationally design and successfully repurpose
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