← RegWatch
HomeRules

Safety Assessment of Genome Editing in Human Gene Therapy Products Using Next-Generation S

The Food and Drug Administration (FDA or Agency) is announcing the availability of a draft document entitled "Safety Assessment of Genome Editing in Human Gene Therapy Products Using Next-Generation Sequencing; Draft Guidance for Industry." The draft document provides recommendations for next-generation sequencing (NGS

AgencyHealth and Human Services Department, Food and Drug Administration
Document typeNotice
Published2026-04-15
SummaryThe Food and Drug Administration (FDA or Agency) is announcing the availability of a draft document entitled "Safety Assessment of Genome Editing in Human Gene Therapy Products Using Next-Generation Sequencing; Draft Guidance for Industry." The draft document provides recommendations for next-generation sequencing (NGS)-based methods used in nonclinical studies that will likely be needed to support initiation of clinical trials of investigational human genome editing (GE) products.
Document number2026-07285
Official recordhttps://www.federalregister.gov/documents/2026/04/15/2026-07285/safety-assessment-of-genome-editing-in-human-gene-therapy-products-using-next-generation-sequencing

🔍 Search all rules →