18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Im
The goal of this open, single-center, prospective, randomized, clinical study is to compare imaging with \[18F\]fluoromethyl-dimethyl-2-hydroxyethylammonium (18F-choline) positron-emission-tomography - computed-tomography, 18F-ch-PETCT, to conventional imaging with ultrasonography and sestamibi scintigraphy in localizi
| Condition(s) | Primary Hyperparathyroidism |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The goal of this open, single-center, prospective, randomized, clinical study is to compare imaging with \[18F\]fluoromethyl-dimethyl-2-hydroxyethylammonium (18F-choline) positron-emission-tomography - computed-tomography, 18F-ch-PETCT, to conventional imaging with ultrasonography and sestamibi scintigraphy in localizing diseased parathyroid glands in patients diagnosed with primary hyperparathyroidism, pHPT. The question this study aims to answer is: can 18-F-ch-PET-CT more precisely localize diseased parathyroid glands in patients with pHPT before surgery? The objective of the study is to help improve precision in parathyroid surgery, thereby increasing cure rates, minimizing complications, and shortening operation times. |
| Who can participate | Inclusion Criteria: Proven primary hyperparathyroidism Indication for surgery Adult (\>18 years) Exclusion Criteria: Inability to give informed consent Allergy to contrast Pregnancy and breastfeeding |
| Ages | 18 Years |
| Sex | All |
| Lead sponsor | Region Skane |
| Locations | Lund, Sweden |
| Start date | 2023-01-01 |
| NCT ID | NCT07138820 |
| Official listing | https://clinicaltrials.gov/study/NCT07138820 |