A Biorepository of Multiple Allergic Diseases (MADREP) With Longitudinal Follow-Up
Background: Allergic or sinus diseases can affect the skin, sinuses, airways, and other parts of the body. Examples include pollen and environmental allergies, food allergies, asthma, and eczema. To learn more about how to prevent and treat these diseases, researchers need to study data, blood, fluid, and tissue sample
| Condition(s) | Allergy, Sinus Disorders, Atopic Diseases, Asthma, Allergic Rhinitis, Atopic Dermatitis, EoE, Drug a |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | Background: Allergic or sinus diseases can affect the skin, sinuses, airways, and other parts of the body. Examples include pollen and environmental allergies, food allergies, asthma, and eczema. To learn more about how to prevent and treat these diseases, researchers need to study data, blood, fluid, and tissue samples from people affected by them. Objective: To collect data, blood, fluid, and tissue samples from people with allergic or sinus diseases. Eligibility: People aged 3 to 100 years with allergic or sinus diseases. Design: Participants will have at least one clinic visit, and most participants will have a baseline visit, annual visit, and an end of study visit. The duration of the study is 1 to 3 years. During the first clinic visit, the following procedures will be done to colle |
| Who can participate | * INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: 1)Aged 3 to 100 years. 2a) Suspected or confirmed allergic, atopic, respiratory, or nasal/sinus disorder or have suspected or confirmed history of an immune dysregulatory disorder, OR 2b) Have a clinical history of an immediate hypersensitivity reaction to aeroallergens, food, insect stings, or medications. 3\) Able to provide informed consent. 4\) Have or are willing to obtain a non-NIH primary physician who will manage all health conditions and be responsive for emergency medical treatment, if required. 5\) Willing to allow storage of blood, skin swabs, nasal fluid/brushings, bodily fluids, and other clinically appropriate tissue specimens or data generated d |
| Ages | 3 Years to 100 Years |
| Sex | All |
| Lead sponsor | National Institute of Allergy and Infectious Diseases (NIAID) |
| Locations | Bethesda, Maryland, United States |
| Start date | 2025-01-28 |
| NCT ID | NCT06732414 |
| Official listing | https://clinicaltrials.gov/study/NCT06732414 |