A Combined Multidomain Intervention to Prevent Cognitive Decline Associated With Cardiovas
The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors.
| Condition(s) | Aging, Cardiovascular Risk Factor |
|---|---|
| Status | Recruiting |
| Phase | NA |
| Study type | Interventional |
| Summary | The ACTIONcardioRisk trial is designed to investigate the effect of aerobic and progressive resistance training exercises combined with cognitive training, on neurocognitive functioning of sedentary older adults with and without cardiovascular risk factors. |
| Who can participate | Inclusion Criteria: * Adult aged 60 and older, * Normal or corrected vision and normal hearing for their age range, * No cognitive impairment (Mini-Mental State Examination - MMSE ≥ 25), * Inactive (\< 150 min of physical activity per week). Exclusion Criteria: * MMSE ≤ 24 or diagnosis of dementia, * Uncontrolled psychological / psychiatric condition within the past 6 months, * Neurological disease, * Severe exercise intolerance, * Respiratory disease (e.g., asthma, COPD), * Excessive alcohol consumption (\> 15 drinks/week), * Documented cerebral, peripheral or coronary atherosclerotic disease, * Chronic systolic or diastolic heart failure, * Symptomatic aortic stenosis, * Atrial fibrillation, * Automatic implantable defibrillator or permanent pacemaker, * Malignant exertional arrhythmias, |
| Ages | 60 Years |
| Sex | All |
| Accepts healthy volunteers | Yes |
| Lead sponsor | Louis Bherer |
| Locations | Montreal, Quebec, Canada |
| Start date | 2021-09-01 |
| NCT ID | NCT04962061 |
| Official listing | https://clinicaltrials.gov/study/NCT04962061 |