A Multi-center Open Label Prospective Study on Early Initiation of Targeted-release Formul
To observe of the efficacy and safety of early initiation of budesonide enteric coated capsules in the treatment of primary IgA nephropathy.
| Condition(s) | IgA Nephropathy (IgAN), Early Initial Therapy |
|---|---|
| Status | Recruiting |
| Study type | Observational |
| Summary | To observe of the efficacy and safety of early initiation of budesonide enteric coated capsules in the treatment of primary IgA nephropathy. |
| Who can participate | Inclusion Criteria: 1. Target patients aged 18-75, including those aged 18 and 75 2. Primary IgA nephropathy diagnosed by renal biopsy within 3 months 3. eGFR≥30ml/min/1.73m2 4. 24-hour urine protein ≥ 1.0g/d, or UPCR ≥ 0.8 g/g 5. Sign informed consent Exclusion Criteria: 1. Including but not limited to secondary IgAN caused by allergic purpura, systemic lupus erythematosus, cirrhosis, rheumatoid arthritis, and ankylosing spondylitis 2. Patients who have received kidney transplantation or dialysis 3. Patients with other glomerular diseases (such as C3 glomerular disease and/or diabetes nephropathy) and nephrotic syndrome (i.e. proteinuria\>3.5 g/d, serum albumin\<3.0 g/dl, with or without edema) 4. Patients with acute, chronic, or potential infectious diseases, including hepatitis, tubercu |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Lead sponsor | Sichuan Provincial People's Hospital |
| Locations | Chengdu, Sichuan, China |
| Start date | 2024-10-30 |
| NCT ID | NCT06676007 |
| Official listing | https://clinicaltrials.gov/study/NCT06676007 |